This family contains pollen-specific proteins of about 30 kDa in size and unknown biological function, which were found only in grass species from the subfamily Pooideae [1]. A ribonuclease activity was reported for Phl p 5 from timothy grass [2].
Group 5 grass pollen allergens are major allergens, which elicit IgE responses in 65% to 85% of grass pollen-allergic patients [1]. Basic members of this family were originally termed group 9. Group 6 grass pollen allergens are major allergens of about 13 kDa, which are similar and cross-reactive to the C-terminal domain of group 5 allergens, but lack their N-terminal domain.
Family-defining Pfam domains (at least one of these domains is present in each family member):
| Pfam domain | Pfam clan | ||
| PF01620 | Ribonuclease (pollen allergen) | - | |
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