Blue (type-1) copper proteins are small proteins which bind a single copper atom and which are characterized by an intense electronic absorption band near 600 nm. The best known members of this family are the plant chloroplastic plastocyanins, which exchange electrons with cytochrome c6, and the distantly related bacterial azurins, which exchange electrons with cytochrome c551 [1].
The only allergenic member of this family is Amb a 3 from ragweed pollen [2].
Family-defining Pfam domains (at least one of these domains is present in each family member):
| Pfam domain | Pfam clan | ||
| PF00127 | Copper binding proteins, plastocyanin/azurin family | CL0026 | Multicopper oxidase-like domain |
| PF02298 | Plastocyanin-like domain | CL0026 | Multicopper oxidase-like domain |
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