Table 1.pdf

Donor characteristics

Figure 1.jpg

Manually microdissected unstained glomeruli
from a wedge transplant kidney
biopsy (print magnification 200x)

Table 2.pdf

Significant features
TI CAD vs LIV (p<0.05)

Figure 2.pdf

Unsupervised hierarchical clustering of LIV
vs CAD microdissected glomeruli and tubuli.

Webtable 1.pdf

Significant genes
separating TI from G (SD >1.6)

Webfigure 1.pdf

Correlation between independently processed samples (from RNA isolation to array readout)
from the same biopsy specimen using either all features or only those that were more than 0.3 SDs differentially regulated on all arrays.

Webtable 2.pdf

Number of features using seven different SDs (ranging from 0.8 to 2.0)
and the 80 % filter (sequences needed to be present in at least 80 % of all arrays)
or unfiltered data.

Webfigure 2.pdf

Dendrograms similar to figure 2 but with
different SDs of >1.0 and >1.6.

Webtable 3.pdf

Functional roles
differentiating CAD
from LIV in TI (p<0.1)

Webfigure 3.pdf

Validation of array experiments with TaqMan-PCR for six selected genes of different GO-term groups.
Numbers represent log2 of reference expression (Universal human reference RNA, Stratagen).
Blue - array and red - PCR reading (mean, SD-bars of triplicates).

Webtable 4.pdf

Number of putative consensus
transcription factor binding sites
(matrices) found in the 62 upstream
sequences (500 bp) separating
TI from G

Webfigure 4.jpg

Hierarchical clustering of promotor sequences
separating the G from TI measured as bitstring
distance (Tanimoto coefficient)